Sr Principal Engineer - MES

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. This is an opportunity you don’t want to miss! Lilly is entering an exciting period of growth, and we are committed to delivering innovative medicines to patients around the world. Lilly is investing to create several new state-of-the-art manufacturing sites. These brand-new facilities will utilize the latest technology for API Manufacturing and will include several platforms including Vaccines, Radio Therapy and Gene Therapy Drug Substance Manufacturing. This is an exciting once-in-a-lifetime opportunity to help build and operate a new site. These new API sites will be built using the latest high-tech equipment, advanced highly integrated and automated manufacturing systems, and have a focus on minimizing the impact to our environment. What You’ll Be Doing : You will be part of Tech at Lilly MQ (Manufacturing and Quality), an organization that drives manufacturing operational excellence and productivity efforts through utilization of technology. Tech at Lilly MQ strives to enable the making of medicine “with safety first and quality always”. The MES Sr Principal Engineer will play a crucial role in delivering the Manufacturing Execution Systems through common modules that enable manufacturing sites to deliver world class performance. The role encompasses responsibility for both the architectural and technical components of the Manufacturing Execution Systems (MES) solution. This involves providing expert guidance and oversight in the design, implementation, and optimisation of MES architecture to ensure it aligns with the organisation’s strategic objectives and operational requirements. A key part of the role is to establish and maintain the direction for Solution Architecture in collaboration with the global Group. This includes implementing defining standards, best practices, and technical frameworks that steer the development and evolution of the MES modules, ensuring consistency, scalability, and reliability across all manufacturing sites. How You’ll Succeed: Utilizes solid understanding of Manufacturing and Quality business processes to anticipate MES short term and future needs from an IT Architecture standpoint. Works with global Architects, Enterprise Architects, local IT teams and other global teams to identify solutions to complex problems related to MES. Sets direction through the formation of a strategic roadmap and evolution of the site design for API MES solution and systems interfaced to MES. Collaborates, influences and/or leads the definition of global IT support and/or delivery processes. Provides deep technical knowledge, monitors solution delivery projects for compliance with the defined reference architecture and proposes and facilitates proof-of-concepts to enable clarity around future state direction. Collaborates with Enterprise Architects to research, identify, test, certify, select and introduce innovative technology products required for solution development and delivery. Collaborates with the Data Management teams to ensure understanding of, and alignment with Data Architecture Standards Actively collaborates with Cybersecurity and Protect Lilly teams to introduce operating principles for MQ IDS MES systems, interfaces and architecture (e.g. proper patching process, LCM, software version control).